Product Description
FUNCTIONSCoenzyme Q10 is a fat soluble nutrient that is poorly soluble in water and is not well absorbed when taken orally. Coenzyme Q10 is an important rate-limiting nutrient that is a cofactor in the mitochondrial electron transport chain, the biochemical pathway in cellular respiration from which adenosine triphosphate (ATP) and metabolic energy is derived. Since nearly all cellular activities are dependent upon energy, coenzyme Q10 is essential for the health of all human tissues and organs.
Given the strength of the science that has been emerging for the use of supplemental CoQ10, it is important to ensure that optimal CoQ10 levels are achieved in the blood following supplementation. Well-CoQ10 is unique among coenzyme Q10 products as it utilizes the patented VESIsorb® technology to deliver coenzyme Q10. When mixed with an aqueous system, this patented technology results in the formation of a nano-colloid containing solubilized CoQ10. This association colloid delivery system contains a highly uniform distribution of droplets that are less than 100 nm in diameter. The size and structure of these droplets allow for enhanced solubility and absorption of coenzyme Q10 (figure 1). This image represents the structure of a nano-colloid droplet which consists of a monolayer with the coenzyme Q10 contained within the core. The formation of the colloidal system upon contact with an aqueous environment (such as the lumen of the intestine) enables the solubilized CoQ10 to more easily diffuse across the unstirred water layer that is present between the enterocyte and the lumen of the intestine (figure 2). One can demonstrate the enhanced solubility of the CoQ10 contained in Well-CoQ10 by placing a capsule in warm water. Once the capsule opens, the contents can be easily mixed with the water, resulting in the formation of the association colloid. There is no separation of oil and water phases as is typical with more traditional CoQ10 delivery systems.
In a clinical study in humans, supplementation with CoQ10 utilizing the patented VESIsorb® technology resulted in greater absorption compared with other CoQ10 products (figure 3).
INDICATIONS Well-CoQ10 may be a useful dietary adjunct for individuals wishing to supplement their diets with a highly absorbable form of CoQ10.
SUGGESTED USE Adults take 1 Caplique™ daily or as directed by your healthcare professional.
SIDE EFFECTS No adverse side effects reported.
STORAGE Store in a cool, dry place, away from direct light. Keep out of reach of children.
INDICATIONS Well-CoQ10 may be a useful dietary adjunct for individuals wishing to supplement their diets with a highly absorbable form of CoQ10.
SUGGESTED USE Adults take 1 Caplique™ daily or as directed by your healthcare professional.
SIDE EFFECTS No adverse side effects reported.
STORAGE Store in a cool, dry place, away from direct light. Keep out of reach of children.
References
Cooke M, Et al. Effects of acute and 14-day coenzyme Q10 supplementation on exercise performance in both trained and untrained individuals. J Int Soc Sports Nutr. 2008 Mar 4; 5:8. Folkers K, Simonsen R. Two successful double-blind trials with coenzyme Q10 (vitamin Q10) on muscular dystrophies and neurogenic atrophies. Biochim Biophys Acta 1995;1271:281-6. Nicolson GL, Conklin KA. Reversing mitochondrial dysfunction, fatigue and the adverse effects of chemotherapy of metastic disease by molecular replacement therapy. Clin Exp Metastasis. 2008; 25 (2): 161-9. Epub 2007 Dec 5. Tiano L, Belardinelli R, Carnevali P, Principi F, Seddaiu G, Littarru GP. Effect of coenzyme Q10 administration on endothelial function and extracellular superoxide dismutase in patients with ischaemic heart disease: a double-blind, randomized controlled study. Eur Heart J. 2007 Sep; 28 (18): 2249-55. Epub 2007 Jul 19. Tran UC, Clarke CF. Endogenous synthesis of coenzyme Q in eukaryotes. Mitochondrion. 2007 Jun; & Suppl: S62-71. Epub 2007 Mar 30. Xian-Liu Z, Artmann, C. Relative Bioavailability Comparison of Different Coenzyme Q10 Formulations with a Novel Delivery System.Altern Ther Health Med 2009 Mar-Apr; 15(2):42-46.Also Recommended
Contact us for more product recommendations!








